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Cefoperazone & Sulbactam

Cefoperazone & Sulbactam

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Cefoperazone & Sulbactam

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Kezone-S-Forte
In normal infection- 1.5-3g in severe or refractory infevtions-12 g every 12 hours in equally divided doses
Normal Infection-30-60mg/kg/day in serious or refractory infections 240 mg/kg/day in 2 or 4 equally divided doses

Yes

 

Product name

Composition

Indication/s

Strengths

Packing

Kezone-S-Forte

Cefoperazone+Sulbactam (2:1)

IAI, PID, UTI, VAP, Sepsis, febrile neutropenia, renally impaired ICU patients, Prophylaxis in Pre / Post Operative Infections

1.5g

1 Vial

3.0g

1 Vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Kezone-S-Forte (Cefoperazone & Sulbactam (2:1) 1.5g / 3 g Vials)

Store below 25ºC. Protect from light

24 hr if controlled at 15ºC to 25ºC 5 days if controlled at 2ºC to 8ºC 3 weeks if controlled at -20º to -10ºC For intravenous infusion, each vial of sulbactam/cefoperazone should be reconstituted with the appropriate amount of 5% dextrose, 0.9% sodium chloride injection or sterile water for injection as mentioned above and then further diluted to 20ml with the same solution followed by administration over 15-60 mins. Lactated Ringer's solution is a suitable vehivle for intravenous infusion. However not for initial reconstitution. For intravenous inj. each vial should be reconstituted as above and administered over a minimum of 3 mins.
5% Dextrose in Water,               5% Dextrose in 0.225% Saline,       5% Dextrose in normal saline,       0.9% NaCl injection