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Doripenem 500mg Injection

Doripenem 500mg Injection
Doripenem 500mg Injection
Product Code : 201
Product Description

Doripenem 500mg Injection


Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Dorvo

500 mg by IV infusion for 1 hour in every 8 hours

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Yes


Product name

Composition

Indication/s

Strengths

Packing

Dorvo

Doripenem

cIAI, UTI including pyelonephritis

500mg

1 Vial


Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Dorvo (Doripenem 500mg Vial)

Store at 25ºC; excursions are permitted to 15ºC-30ºC

Upon constitution with SWFI or 0.9 % NaCl the suspension may be held for lhr. prior to transfer & dilution in the infusion bag. If diluted in 0.9% NaCl, Stable for 12hrs at 25ºC & for 72 hrs isf stored at 2ºC-8ºC If diluted in 5 % Dextrose stable for 4 hrs & for 24 hrs if stored at 2-8ºC.

IV infusion: Constitute the 500mg vial with 10ml of sterile water for inj. Or 0.9 % NaCl inj. & gently shake to form a suspension . The resultant conc. Is approx. 50 mg/mL. Withdraw the suspension using a syringe with a 21 gauge needle and add it to an infusion bag containing 100mL of normal saline or 5% dextrose; gently shake until clear. The final infusion solution conc. Is approximately 4.5 mg/mL.

0.9% NaCl, 5% dextrose


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