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Lyocarb

Lyocarb

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Lyocarb

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Lyocarb
As single agent - 360mg/m² IV every 4 weeks.  As combination therepay - 300mg/m² IV every 4 weeks
Dose & duration varies as per indication from 300-600mg/m²
Yes

 

Product name

Composition

Indication/s

Strengths

Packing

Lyocarb

Lyophilized Carboplatin

Advanced ovarian carcinoma

150mg

1 Vial

450mg

1 Vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Lyocarb (Lyophilized Carboplatin 150mg & 450mg Vials)

Store at 25ºC

Stable for 8hrs when stored at room temperature
Reconstitute 150mg vial with 15ml and 450mg vial with 45ml of diluent to make final conc. of 10mg/ml. It can be further diluted to 2mg/ml to as low as 0.5mg/ml
Reconstituting agent - Sterile water for injection, 5% dextrose and normal saline Diluting agent - 5% dextrose and normal saline