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Lyoplat

Lyoplat

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Lyoplat

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Lyoplat 85mg/m² given IV over atleast 2hrs
Safety and efficacy of oxaliplatin has not been established.
Yes

 

Product name

Composition

Indication/s

Strengths

Packing

Lyoplat

Lyophilized Oxaliplatin

Adjuvant treatment of Stage III Colon Cancer

50mg

1 Vial

100mg

1 Vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Lyoplat (Lyophilized Oxaliplatin 50mg & 100mg Vials)

Store at 25ºC

After reconstitution the solution may be stored up to 24hrs at 2-8ºC. After dilution the shelf life is 6hrs at room temp. or up to 24hrs at 2-8ºC Reconstitution - Add 10ml (for 50mg vial) and 20ml (for 100mg vial) of water for injection.                              Dilution - Reconstituted solution should be further diluted in an infusion solution of 250-500ml of 5% dextrose. infuse for over 2 - 6hrs.
Reconstituting agent - Water for injection, 5% dextrose Diluting agent - 5% dex