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Methylprednisolone Sodium Succinate 500mg

Methylprednisolone Sodium Succinate 500mg

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Methylprednisolone Sodium Succinate 500mg

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Sol-U-Pred

Anti-inflammatory -10-40mg IV over a period of several minutes. High dose therapy - 30mg/kg administered IV over at least 30 minutes. Dose may be repeated every 4-6hrs. for 8 hrs.Multiple Sclerosis -200mg prednisolone for a week followed by 80mg every other day for a months.


Dosage may be reduced for infants and children but should be governed more by the severity of the condition and response of the patient than by age or size. It should not be less than 0.5mg per kg every 24hrs.

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Product name

Composition

Indication/s

Strengths

Packing

Sol-U-Pred

Methylprednisolone Sodium Succinate

Multiple sclerosis, Antiinflammatory / Immunosuppressant agent,

500mg

1 Vial

1g

1 Vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Sol-U-Pred (Methylprednisolone Sodium Succinate 500mg / 1 g Vials)

Protect from light, store at controlled room temperature, 20oC-25oC

Store reconstituted solution at controlled room temperature, 20oC-25oC. Use within 48 hrs after mixing.

When reconstituting use only the accompanying Diluents i.e. acteriostatic water 8ml for 500mg & 16ml for l g. therapy may be initiated by administering Sol-U-Pred sterile powder intravenously over period of at least 5 mins. (e.g. doses up to & including 250mg) to at least 30 mins. (e.g. doses exceeding 250mg) subsequent does may be withdrawn and administered similarly. if desired, the medication may be administered in dilute solutions by admixing the reconstituted product with dextrose 5% in water, normal saline, dextrose 5% in 0.45% or 0.9% NaCl. 

5% Dextrose in water,

0.9NaCl,

5% Dextrose in 0.45% or 0.9NaCl