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Onconase

Onconase

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Onconase

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Onconase
50 to 200 KU/Kg body weight daily or every alternate day.
200 IU/Kg/day IV x 28 days
yes

 

Product name

Composition

Indication/s

Strengths

Packing

Onconase

L-Asparaginase

Acute Lymphocytic leukemia

5000 KU

1 Vial

10000 KU

1 Vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Onconase (L-Asparaginase 5000 KU/10000 KU injection

Store at 2oC-8oC

Use with in 8 hrs
Reconstitute by adding 5ml of water for inj. for IV and 2ml for IM to a vial containing 10000 KU of L-asparaginase and shake gently to dissolve. For IV administration the dose required should be removed containing 2000 KU/ml and must be further diluted with 200-500ml of 0.9% NaCI or 5% Glucose.
Water for injection, 5% Glucose, 0.9% NaCI.