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Rinotec

Rinotec

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Rinotec

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Rinotec
125 mg/m2 IV or 90 min, d 1,8,15,22 then 2-wk rest. 350mg/m2 IV over 90min, once every 3 wks

No

 

Product name

Composition

Indications

Strengths

Packing

Rinotec

Irinotecan HCI

Metastatic carcinoma of the colon of rectum

40 mg/2ml

1 vial

100mg/5ml

1 vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Rinotec (Irinotecan Hydrochloride 40mg and 100mg Vials)

Store below 25oC. Protect from light. Do not Freeze

After dilution solution is stable for 24hrs at room temperature and 48hrs at 2oC-8oC
It is diluted by 5% dextrose p to a conc. of 0.12-2.8 mg/ml. Infuse for over 10 minutes
5% Dextrose (Preferred) 0.9% NaCI solution.