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Sulbactam & Cefoperazone for Injection

Sulbactam & Cefoperazone for Injection
Sulbactam & Cefoperazone for Injection
Product Code : 209
Product Description

Sulbactam & Cefoperazone for Injection


Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Kephazon-S

2-4 g/day BID, Max. upto 8 g per day

40-80 mg/kg/day in 2-4 equal divided doses

Yes


Product name

Composition

Indication/s

Strengths

Packing

Kephazon-S

Cefoperazone Sodium / Sulbactam (1:1)

RTI, Peritonitis & other IAI, Bacterial Septicemia, SSTI, PID, Endometritis, and Other Infections of the Female Genital Tract, UTI, Enterococcal infections

1 g

1 Vial

2g

1 Vial


Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Kephazon-S (Cefoperazone/Sulbactam 1g/2g Vials)

Store below 25ºC

24 hr if controlled at 15ºC to 25ºC, 5 days if controlled at 2ºC to 8ºC, 3 weeks if controlled at -20º to -10ºC

For intravenous infusion, each vial of sulbactam/cefoperazone should be reconstituted with the appropriate amount of 5% dextrose, 0.9% sodium chloride injection or sterile water for injection as mentioned above and then further diluted to 20mL with the same solution followed by administration over 15-60 mins. Lactated Ringer's solution is a suitable vechile for intravenous infusion, however not for initial reconstitution. For intravenous inj. Each vial should be reconstituted as above and administered over a minimum of 3 mins.

5% Dextrose Injection (USP) 5% Dextrose and 0.9% Nacl Injection (USP) 5%Dextrose and 0.2% NaCl Injection (USP) 10% Dextrose Injection (USP) Sterile Water for Injection


Prep of solution :


Total dosage (gm)

Equivalent dosage of sulbactam+cefoperazone (gm)

Total Volume of Reconstituted Solution (mL)

Maximum final concentration (mg/mL)

1.5

0.5+0.5

4.0

125+125

3

1.0+1.0

8.0

125+125


 

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