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Topotec

Topotec

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Topotec

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Topotec 1.5 mg/m² by IV infusion over 30 minutes daily for 5 consecutive days, starting on day 1 of a 21 day course
----------- Required in renal impairment

 

Product name

Composition

Indication/s

Strengths

Packing

Topotec

Topotecan

Cervical cancer, Ovarian Cancer, Small cell lung cancer

2.5mg

1 Vial

4mg

1 Vial

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Topotec (Topotecan 2.5mg / 4mg Vials)

Store at room temp. between 20o-25oC away from light and moisture

Should be used immediately after reconstitution
Should be reconstituted with 2.5ml and 4ml of sterile water for inj. for 2.5mg & 4mg vial resp. to achieve a final conc. of 1mg/ml, then further dilute it with 0.9% NaCl or 5% Dextrose to 0.01mg - 0.5mg/vial. Infuse for over 30 minutes
0.9% NaCl, 5% Dextrose