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Uniphos

Uniphos

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Uniphos

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Uniphos Inj : 40 - 50 mg/kg IV in divided doses over a period of 2-5 days.     Tab : 1-5 mg/kg daily.
40 - 50 mg/kg IV in divided doses over a period of 2-5 days may be repeated every 2-4 weeks
No

 

Product name

Composition

Indication/s

Strengths

Packing

Uniphos

Cyclophosphamide

Malignant Disease : Malignant Lymphomas (Stage III and IV), Hodgkin's Lymphoma, Hodgkin Disease, Multiple myeloma, Leukemia, Mycosis Fungoides, Non-Malignant Disease: Biopsy proven minimal change nephrotic syndrome in children

200mg

1 Vial

500mg

1 Vial

1g

1 vial

50mg

1x10 Tabs

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Uniphos (Cyclophosphamide 1g, 500mg, 200mg Vials & 50mg Tablets)

Storage at or below 25oC should be protected from temperature above 30oC

Reconstituted solution is chemically and physically stable for 24 hours at room temp or for six days in the refrigerator.

Doses of less than 1g should be diluted in 100ml NS & infused 15 minutes. Doses of 1000mg - 2000mg should be diluted in 250ml NS & infused 30 minutes. Doses of more than 2g should be diluted in 250ml - 500ml NS & infused 30 - 60 minutes. High doses (2000mg/m² or greater) should be diluted in 1000ml NS & infused for over 1-4hrs

Dextrose and NaCl injection (5% and 0.9%) NaCl solution U.S.P (0.45% NaCl), LR, D5LR