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Voriconazole for Injection

Voriconazole for Injection

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Voriconazole injection

Product

Adult dose

Pediatric dose

Adjustment in Renal / Hepatic Impaired patients

Vonaz

Loading Dose: 6mg/kg every 12 for first 24 hours. Minatenance dose: 3-4mg/kg every 12 hours IV or 200mg every 12 hour orally

>12 Years-Same As Adults 2 years and older-6mg/kg IV every 24 hours for 2 dosage followed by 4 mg/kg IV every 24 hours

Yes

 

Product name

Composition

Indication/s

Strengths

Packing

Vonaz

Voriconazole

Invasive Aspergillosis, Candidmia, Esophageal candidiasis Fungal infections caused by scedosporium apiospermum

200mg

1 vIAL

50mg

1 x 4 Tabs

200mg

1 x 4 Tabs

 

Product name

Storage

Stability after reconstitution

Prep of solution

Diluent

Vonaz (Voriconazole 200mg tab & 200 mg vial)

Store between 15°C-30°C away from heat light and mositure

Vial to be used with in 24hrs after reconstitution between 2°C-8°C

Reconstitute 200mg vial with 19ml of water for injection to obtain an extractable volume of 20ml of clear concentrate containing 10mg/ml of voriconazole further diluent to obtain a conc. Of 5mg/ml or less. Infuse over 1-2 hrs or at max. rate of 3mg/kg/hrs

9mg/ml (0.9% NaCl USP Lactated ringer's USP 5% Dextrose 7 Lactated ringer's USP, 5% Dextrose & 0.45% NaCl USP 5% Dextrose USP, 5% Dextrose & 20 mEq potassium chloride USP, 0.455 NaCl USP, 5% Dextrose & 0.95 NaCl USP